Are pregnancy complications increased in poor responders? Ovaryen stimulasyona kötü yanıt veren hastalarda gebelik komplikasyonları artmış mıdır?

Address for Correspondence / Yazışma Adresi: Uzm. Dr. Huriye Ayşe Parlakgümüş, Başkent Üniversitesi Seyhan Uygulama Hastanesi, Cemal Paşa Mah. Barajyolu, 01110 Adana, Turkey Phone: +90 322 458 68 68/2203 e.mail: [email protected] doi:10.5152/jtgga.2011.01 Objective: To investigate whether pregnancy complications are increased in poor responders to ovarian stimulation in IVF treatment. Material and Methods: We reviewed the antenatal follow up and birth records of 26 poor responders to ovarian stimulation and 125 normoresponder patients in an IVF program. Results: Eighty nine (71.2%) of the normoresponders and 22 (84.6%) of the poor responders had no pregnancy complications. Gestational diabetes was present in 18 (14.4%) of the normoresponders and 3 (11.5%) of the poor responders. Seven of the normoresponders had placenta previa (5.6%). Two of the normoresponders (1.6%) had pregnancy induced hypertension. Two (1.6%) of the normoresponders had preeclampsia. One patient from each group had fetal anomaly (3.8% for poor responders vs. 0.8% for normoresponders). Cholestasis of pregnancy was present in two of the normoresponders (1.6%) and the 2 patients (7.7%) who delivered prematurely also belonged to this group. Conclusion: Our results revealed that pregnancy complications were not increased in patients with a reduced ovarian reserve when compared to their age matched counterparts. (J Turkish-German Gynecol Assoc 2011; 12: 1-3)